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Important Safety KPV Oral Capsules

KPV Oral Capsules (Compounded Lysine-Proline-Valine)


Important Safety Notice



THIS IS A CUSTOM PRESCRIPTION MEDICATION INTENDED ONLY FOR YOU.

What is KPV?

KPV (lysine-proline-valine) is a three-amino-acid peptide supplied as a compounded oral capsule. It is being investigated for effects on inflammatory pathways; clinical benefits in humans have not been established.


Important: KPV is NOT FDA-approved for any use. This compounded product has not been reviewed by FDA for safety, effectiveness, or quality.


Evidence status: Human studies of oral KPV are very limited. Its long-term safety, pharmacokinetics, and appropriate treatment duration are not established.


What it is studied for: Laboratory and animal research has examined inflammatory signaling and intestinal
health. These findings do not establish that KPV treats any human disease.

Strength: Refer to the strength and ingredients on your prescription label.

Note: This summary does not contain all possible safety information. It is not a substitute for advice from your healthcare provider. Always talk to your doctor or pharmacist before using this medication.

How to Take KPV Capsules

  1. Check the strength and directions on your prescription label.
  2. Swallow the prescribed capsule by mouth with water.
  3. Take with food if directed by your pharmacist or prescriber.
  4. Do not exceed your prescribed daily dose.
  5. If you have difficulty swallowing the capsule, ask your pharmacist before opening it.

Important Usage Notes

  • Dose: Follow your prescription label.
  • Timing: Take at the time recommended by your prescriber. No evidence-based optimal time is established.
  • Missed dose: Contact your pharmacist for individualized instructions. Do not double doses.
  • Administration: Take by mouth only. Do not share medication with others.
  • Monitoring: Report new or concerning symptoms to your healthcare provider.
  • Storage: Store at 20–25°C (68–77°F), tightly closed, protected from moisture, heat, and light, unless the pharmacy label states otherwise.
  • Source: Use only medication dispensed by a licensed pharmacy for your prescription.

Who Should NOT Take KPV


Do not use KPV if you:


  • Have a known allergy to KPV or any capsule ingredient.
  • Have previously experienced a serious reaction to this formulation.
  • Have not confirmed the product strength or directions with your pharmacist.
  • Are pregnant, planning pregnancy, or breastfeeding unless your clinician has specifically reviewed the unknown risks.
  • Are giving this medication to a child without explicit specialist direction; pediatric safety has not been established.

Important Warnings

Limited Safety Data

  • Human safety data for oral KPV are insufficient to define the frequency or severity of adverse effects.
  • Long-term effects, reproductive safety, metabolism, and drug interactions have not been adequately characterized.

Cardiovascular and Other Systemic Effects

  • KPV-specific effects on blood pressure, heart rhythm, and bleeding risk have not been established.
  • Seek medical assessment for new fainting, severe dizziness, chest pain, or unexpected bleeding.

Immune and Allergic Reactions

  • Allergic reactions are possible with any medication or formulation ingredient.
  • Stop taking the capsules and seek emergency help for facial or throat swelling, wheezing, or difficulty breathing.

Neurologic and Behavioral Effects

  • • Effects of KPV on mood, alertness, or neurologic function in humans are not established.
  • Tell your clinician about neurologic or psychiatric conditions and all medications you use.
  • Report unusual or persistent symptoms after starting treatment.

Gastrointestinal Effects

  • Stomach upset or nausea may occur, but reliable human adverse-event rates are unavailable.
  • Contact your clinician for persistent vomiting, severe abdominal pain, or inability to tolerate oral intake.

Other Precautions

Talk to your doctor before taking KPV if you:

  • Have liver or kidney disease, or other significant medical conditions.
  • Take prescription medications, over-the-counter products, or supplements.
  • Are pregnant, breastfeeding, or planning pregnancy.

Alcohol and Cannabis

  • Limit alcohol and avoid cannabis and recreational drugs while using TB-500. How TB-500 interacts with these substances has not been studied.

Drug Interactions


KPV drug interactions have not been adequately studied. Tell your doctor and pharmacist about all medicines and supplements you take.


Always tell all your doctors and pharmacists that you are using TB-500 (subcutaneous injection), especially before starting any new medications or having surgery.

Possible Side Effects

Because human safety studies are limited, the full side-effect profile is unknown. Symptoms listed in the supplied KPV
guide include:


  • Mild gastrointestinal discomfort
  • Nausea
  • Headache
  • Dizziness
  • Changes in appetite (not well characterized)
  • Other unexpected or persistent symptoms


If any side effects become concerning, contact your doctor or call the phone number on your prescription label to speak with a pharmacist.


When to Seek Emergency Medical Help

STOP taking KPV and seek immediate medical attention if you experience:


  • • Difficulty breathing, wheezing, or throat tightness
  • Swelling of the face, lips, tongue, or throat
  • Severe rash or widespread hives with other symptoms
  • Fainting, severe weakness, or confusion
  • Severe or persistent abdominal pain
  • Chest pain or other severe unexplained symptoms
  • Any rapidly worsening or life-threatening reaction

If you take too much, contact your provider or Poison Control at 1-800-222-1222.


Reporting Side Effects

If you experience any serious or unexpected side effects, report them to:


  • Pharmacy / Compounding Hub: Mills Compounding Pharmacy 248-633-2880
  • FDA: 1-800-FDA-1088
  • FDA Online: www.fda.gov/medwatch